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Thromb Haemost 2004; 91(04): 646-654
DOI: 10.1160/TH03-09-0568
DOI: 10.1160/TH03-09-0568
Review Article
Acquired hypercoagulable state in renal transplant recipients
Further Information
Publication History
Received
11 September 2003
Accepted after resubmission
14 January 2003
Publication Date:
06 December 2017 (online)
Summary
Stable renal transplant recipients manifest a chronic hypercoagulable state with an increased risk of thromboembolic complications, which appears to be multifactorial. While this group of patients could present the known risk factors for thromboembolism in the general population (e.g. diabetes, cancer, pregnancy), they may also suffer from other situations which are mostly related to transplantation and are consequently specific to them. Here, we review briefly the clinical aspects and controversies of the most important of these factors including immunosuppressive agents, antiphospholipid antibodies, hyperhomocysteinemia, pre-transplant dialysis modality, and posttransplant erythrocytosis. In addition, other more recent topics including hypercysteinemia, recurrent proteinuria, and acute CMV infection are discussed.
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References
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